Studying strength characteristics of impregnated polymer composition for practical use in the field of purulent surgery 

Ivan M. Efremov, Candidate of medical sciences, associate professor of the sub-department of hospital surgery, anesthesiology, resuscitation, urology, traumatology and orthopedics, Ulyanovsk State University (42 L’va Tolstogo street, Ulyanovsk, Russia), E-mail: efremov-im@rambler.ru
Vladimir I. Midlenko, Doctor of medical sciences, professor, director of Institute of medicine, ecology and physical culture, head of the subdepartment of hospital surgery, anesthesiology, resuscitation, urology, traumatology and orthopedics, Ulyanovsk State University (42 L’va Tolstogo street, Ulyanovsk, Russia), E-mail: kafsvmp@yandex.ru 

Background. Аn antimicrobial polymer composition based on acrylic bone cement and antibacterial drugs in the treatment of patients with chronic osteomyelitis and periimplant infection are widely used in clinical practice. The purpose of the study is to assess the strength characteristics of bone cement based on polymethyl methacrylate (PMMA), impregnated with antibacterial drugs, for axial compression. Materials and methods. Six series of in vitro experiments were performed using CC based on PMMA Synicem1 (France). In each series, after mixing the components of the polymer composition, a disc with a diameter of 45-50 mm and a thickness of 5-7 mm was made by hand. The samples obtained from acrylic CC were tested on an LFM 125 kN electromechanical testing machine (Walter + Bai, Switzerland) with a load in the range of 10-10000 N. Results. The strength of acrylic bone cement Synicem 1 exceeds the permitted strength in accordance with GOST ISO 5833-2011 At the same time, a significant decrease in the strength characteristics of CC Synicem 1 was noted with the addition of antimicrobial drugs in the form of a liquid in series 4 (p <0.0001) and 5 (p <0.0001). Conclusion. The strength characteristics of polymerized samples of acrylic bone cement Synicem 1 correspond to GOST ISO 5833–2011. The mechanical strength of polymerized samples of acrylic bone cement Synicem 1 significantly decreases with the addition of liquid antibacterial components, which must be taken into account in clinical practice. 

bone cement, polymethyl methacrylate, mechanical strength, purulent surgery 

Efremov I.M., Midlenko V.I. Studying strength characteristics of impregnated polymer composition for practical use in the field of purulent surgery. Izvestiya vysshikh uchebnykh zavedeniy. Povolzhskiy region. Meditsinskie nauki = University proceedings. Volga region. Medical sciences. 2022;(2):83–91. (In Russ.). doi:10.21685/2072-3032-2022-2-9